Research Studies

Ophthalmic ResearchOCLI possesses a rich history in the field of ophthalmic clinical research of which we are most proud. Our Long Island eye doctors have been dedicated for decades to innovation in eye care for all. OCLI has had the opportunity to be involved with clinical research trials with companies such as Allergan, Bausch & Lomb, Abbott Medical, Pfizer and Alcon to name a few. Together, major advances in eye care have been made with more effective drugs and improvements in various eye surgical devices and surgical techniques.

OCLI’s list of participating research physicians read like a Who’s Who in ophthalmology. Our doctors’ deep commitment, extensive knowledge, intuitive insight and innovative thinking make them highly sought after for their opinions and hands on participation globally. Their strong collaboration with the eye care research and business community has brought about advances in the treatment of dry eye, corneal disease, retina disease, glaucoma and cataracts.

Please read on to learn more about studies we are currently conducting at OCLI.


Dry Eye

Dry eye disease is a condition in which a person doesn’t have enough quality tears to lubricate and nourish the eye. Tears are necessary for maintaining the health of the front surface of the eye and for providing clear vision. Dry eye is a common and often chronic problem, particularly in older adults. With each blink of the eyelids, tears spread across the front surface of the eye, known as the cornea. Tears provide lubrication, reduce the risk of eye infection, wash away foreign matter in the eye, and keep the surface of the eyes smooth and clear. Dry eyes can occur when tear production and drainage is not in balance.

If you have been diagnosed with dry eye you may be experiencing symptoms such as eyes feeling dry, foreign object sensation in your eye, burning, tearing or even itching. If so you may qualify for a Dry Eye Research Study. OCLI is currently participating in a study to evaluate an investigational drug that can help you combat the symptoms of inflammation due to dry eye disease. All study procedures are covered by the research sponsor at no cost to you or your insurance company.

To determine if you are eligible please contact our Research Department at 516-705-7140.


Glaucoma is a condition of increased pressure within the eyeball. Increased pressure can damage your eye’s optic nerve and can cause gradual loss of sight.  The optic nerve is responsible for sending signals from your retina to your brain, where these signals are interpreted as the images you see. When glaucoma develops, usually you don’t have any early symptoms and the disease progresses slowly. In this way, glaucoma can steal your sight very gradually. Early detection and treatment (with glaucoma eye drops, glaucoma surgery or both) can help preserve your vision.

Glaucoma is often cited as one of the major disease states for which patients are not compliant with their physician-prescribed home treatment. Our current study is examining the impact of managing the disease by reducing the need for patients to remember to take their drops. Instead the use of a sustained release therapy provides a long-term Intraocular Pressure (IOP) lowering result which is crucial to preventing the progression of Glaucoma. All study visits related procedure are covered by the study sponsor, there is no cost to the patient or the patient’s insurance for any study visit.

If you or a loved one is interested, please contact our Research Department at 516-705-7140.

Hyperopia (Farsightedness)

Farsightedness, or hyperopia, is a vision condition in which distant objects can be seen clearly, but close ones do not come into proper focus. Common signs of hyperopia include difficulty concentrating and maintaining a clear focus on near objects, eye strain, fatigue and/or headaches after close work, aching or burning eyes, and irritability or nervousness after sustained concentration.

If you are 40 years of age or older we are currently conducting a clinical trial that may help correct your farsighted through the use of an investigational laser vision treatment. If you currently depend on glasses or contact lenses to correct your hyperopia, this office procedure, which takes approximately 5 minutes to complete, may help.

To determine if you are eligible, please contact our Research Department at 516-593-4026.


A healthy retina is necessary for good vision. The retina is the part of your eye that takes light and turns it into signals for your brain to interpret. This is the part of your eye that confirms how images are viewed. Images are focused here on this thin membranous lining at the back of the eye. The images are focused here and converted to electrical impulses which are carried to the brain by the optic nerve.

Diseases of the retina are common as we age. These diseases can severely impair vision or even cause blindness. If your eye specialist has discussed with you the possibility of having a form of retina disease, OCLI can offer you treatment options. We are currently conducting multiple research studies offering Treatment options for a variety of Retina conditions. These trials offer options for the treatment of Geographic Atrophy, Wet Age-Related Macular Degeneration and Diabetic Macular Edema. All study procedures are cover by the research sponsor at no cost to you or your insurance.

If you would like more information or wish to find out if you are eligible to participate, please contact our Research Department at 516-593-4026.